The Common Side Effects of Centrophenoxine

What is Centrophenoxine?

Most people believe the concept of a smart drug is something out of a science fiction novel. In actuality, a new type of nutritional supplements has emerged that has all the properties of a drug that enhances your concentration, focus, and aids in mental cognition. These are called nootropics, and new types of them are cropping up everywhere with different features – some improve memory while other aid in concentration. One of these is a supplement called Centrophenoxine, a memory booster that also purports to increase your overall brain power. And its popularity is rising due in no small part to the kinds of results it is being observed to induce in those who use it.

Centrophenoxine, also known as Meclofenoxate and by its commercial name Lucidril, is a nootropic supplement that’s touted as having memory enhancing and cognitive focusing properties. It belongs to the cholinergic family of drugs, meaning it contains Acetylcholine that is meant to affect and work in conjunction with the parasympathetic nervous system. There are many cholinergic drugs that have recently been classified as nootropics.

Its chemical structure is similar to Dimethylaminoethanol (DMAE), an organic compound found in food such as fish that acts as a brain booster. Instead of taking DMAE supplements that may have adverse side effects, taking a nootropic such as Centrophenoxine causes chemical reactions in the brain that manufacture Acetylcholine in the body naturally. It’s purported to have beneficial properties such as enhancing memory performance, induce mental stimulation, and improve focus and give the user added energy.


Specifically, Centrophenoxine when ingested acts to optimize thought processes that are linked to memory retention and reasoning. There are two kinds of intelligence: IQ and fluid intelligence – which is the ability to think logically and problem solve. This is links to your working memory, the brain’s ability to recall facts and information while accomplishing mental tasks in real time.

Centrophenoxine works to extend your ability to retain information and thus improve your overall memory and enhance your ability to problem solve thanks to your larger repository of retained information. You remember more, so when you’re trying to solve a problem you now have more information to draw from. By enhancing your brain’s fluid intelligence, Centrophenoxine can actually make it easy for you to learn new skills and procedures and use them when needed. Not only can it help enhance your overall memory, but this nootropic is also suggested to be able to eliminate environmental toxins from the body. Centrophenoxine side effects are unmatched by the nootropic’s extraordinary benefits on the human brain.

Recommended Dosage

Though Centrophenoxine is one of the safest nootropics on the market, taking it within recommended dosages is always encouraged as even the mildest of medical supplements may have an adverse side effect if you exceed these recommendations. It can be taken orally in either powder form or via capsules. Most medical experts those using it as a nootropic recommend starting off with a small dose of about 250mg twice a day – once in the morning and again in the early afternoon. Also, since it has been shown to increase your energy, you may not want to take it too late as this could affect your sleep patterns. For best results, and to avoid the drug’s side effects, take 5-1500 mg per day.

Once you begin to learn how this supplement influences your own personal body chemistry (in other words when you learn whether or not this beginning does is weak or strong enough to affect you in observable ways) then you can begin raising your dosage anywhere from 300 mg at a time to 1000 mg. It all depends on how sensitive your body chemistry is to this nootropic.

In addition to just this supplement by itself, you can also stack it with other cholinergic nootropics to regulate your intake of Centrophenoxine. There are some adverse side effects associated with exceeding the recommended dosage (as will be outlined below) but these are generally mild. If you were to experience any of them, just reduce your dosage or stop altogether to alleviate them. This indicates Centrophenoxine is a nootropic that best when used in cycles rather than continuously to prevent tolerance building and risking an overdose reaction.

Side Effects

The most attractive feature of Centrophenoxine compared to other forms of choline supplements is how mild and relatively safe it is. However, taking more than the recommended dosage based on your previous experience with it can cause some side effects. This usually is the result of taking too much too soon. The side effects may include nausea, headaches, dizziness, fatigue, nervousness, and some jaw clenching if you take way too much too soon. Stop immediate or reduce your dosage if you start experiencing any of these.

Long-Term Effects

Taking Centrophenoxine semi-regularly has been shown to lead to higher overall Acetylcholine levels in the brain and an increase in the production of RNA, one of the molecular acids that are essential to life and aid in the production of proteins in the body.

Not much is known about the mechanism of action in Centrophenoxine, but what is known is that it helps cells carry out protein synthesis at higher rates than normal. This may account for the brain’s increased ability to retain information and store it for future mental tasks. Whatever the cause of increased Acetylcholine levels, this higher choline production acts as a neuroprotectant that reverses the accumulation of potassium in the brain, which has been shown as a damaging by-product of aging. This is why Centrophenoxine is often prescribed for memory loss due to senility.

Short-Term Effects

The short term effects of using Centrophenoxine are subtle at first, but easier to discern once you start upping the dosage. You may experience long term effects like a slower aging brain, but immediately you’ll notice that you remember more information at a faster rate. Also, you may experience an increase in focus and concentration and feel as though you have more energy.


You will first experience an increase in your energy levels upon forty-five minute after taking this nootropic. Next, you will experience an uptake in oxygen levels transmuted to the brain and higher glucose levels. This make account for the increase in energy levels you experience. When learning new skills or task, you’ll also experience an increased ability to remember what you learn and recall more of it. This is why nootropics are often used as study aids for students cramming for a test. Finally, you’ll be able to perform mental and logic tasks faster and easier than before.

What Will I Feel?

Taking Centrophenoxine feels a lot like a sugar high, but without the jittery feel (as long as you stay within recommended dosages) and the inevitable crash later on. Your mood will elevate slightly as you feel more able to accomplish a wider variety of tasks. It will feel as though you’ll be able to accomplish anything you set your mind to as well as increase your confidence levels while taking it. As long as you don’t take more than the recommended dosages, the come-down effect will only be subtle and not as precipitous as other stimulants like caffeine.

How Long Does This Last?

The duration of the effect upon taking it last about half a day, which is why it often recommended that you take one dose in the morning and another in the early afternoon. Make sure you take only as much as needed based on your previous experience with it. Beginners should start off with 250 – 300 mg while those who have noticed their tolerance levels increasing should take more but not exceed 1000 mg as they progress.


There have been a considerable amount of human studies for Centrophenoxine that shows how your intellectual well-being can improve. The main effect that is observed is a reduction in lipofuscin deposits in the nerve cells in the brain. This has mainly been observed in patients with senile dementia as well as otherwise healthy adults. Other experiments have shown a reversal of the reduction of RNA production that occurs with advancing age. Since RNA aids in the turnover of protein and acts as an anti-aging agent, this is significant.

Common Stacks

Stacking Centrophenoxine with other similar nootropics has the effect of increasing the demand for Acetylcholine, which works in conjunction with Centrophenoxine that increasing Acetylcholine production. The most common nootropic stacked alongside it is Piracetam. Piracetam is the most popular nootropic on the market, and it seems to work hand in hand with Centrophenoxine flawlessly. In fact, if you take centrophenoxine but there is not enough choline in your system to induce demand for more Acetylcholine, you may experience headaches because of this. This also means that you will have a limit on the beneficial effects of taking Centrophenoxine alone.

Other Choline Sources

Beside Centrophenoxine, there are many other choline based nootropics that also have similar effects of inducing Acetylcholine production. Alpha GPC is easily the most popular and well-known, but many are unaware of others such as Citicoline or just pure Choline supplement. They have similar properties of Centrophenoxine and are somewhat more effective in producing more acetylcholine, however, they are slightly more potent and require more vigilance to prevent overdosing on them and experiencing adverse side effects.

Online Reviews

Here are some online reviews to give you a better idea of how well it works:

I started taking this in conjunction with pramiracetam so my experiences with Centrophenoxine may be slanted because I do not take it alone….. What I did notice though was my ability to articulate thoughts and speak with more intelligence did increase. I am able to think on my feet more and when someone asks me a question or says something I am able to respond a lot quicker and this response is usually very clever.

Give this some time to work. I have been taking it for a month now and am seeing and feeling some great benefits. I can think clearer and am having fewer and fewer and hardly no need for little reminders all over the place anymore….I also just feel so much better over all. I have seen a decrease in dark spots, and no more little red blood dots all over my skin. I feel and look healthier and will be recommending this to my friends and family

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