Is Pramiracetam Safe Over The Long Term?

What Is Pramiracetam?

Pramiracetam is a drug that is used as a nootropic by tens of thousands of individuals each month looking for a brain boost. Its typical effects work on improving memory, mood, focus, and overall energy levels throughout the day. It can also be used to help improve a person’s memory and brain power. Pramiracetam has been touted to be as much as 30 times more effective than Piracetam and can be taken on a long-term basis with very few ill side effects. Pramiracetam is a very effective and safe smart drug to use and should be used with choline for best effects, and to avoid a pesky “racetam headache.” Pramiracetam does not require a prescription from your doctor to get.


Pramiracetam can improve the memory and attention span in those looking for it. Pramiracetam, as it is as much as 30 times more powerful than the original leading smart drug, Piracetam, is very powerful, and if a powerful choline source is taken with it, such as CDP or Alpha GPC Choline, it can have amazing effects on how the human brain functions. Pramiracetam effects a wide variety of neurotransmitters including dopamine, norepinephrine, and Acetylcholine, but mostly Acetylcholine. Common stacks for Pramiracetam include Adrafinil, CDP choline, Noopept, and Alpha GPC Choline.


The exact dosage that will be prescribed will depend on the severity of the patient’s condition and will be prescribed by a doctor. It is important that you never take more than the recommended dose. You should not need to take more than two 500mg doses in a day.

Side Effects

There are very few reported side effects for Pramiracetam which makes it a very popular drug. Some people have experienced headaches when taking these pills but this can be easily rectified by taking a choline source with the drug. Pramiracetam is used by tens of thousands of individuals worldwide with great success. Always do your own research, reviews, and trials before taking a nootropic, as they can have some side effects if too high of a dosage is taken.

Long-Term Use

Provided that you do not take more than the recommended dose, there is no reason why Pramiracetam cannot be used on a long term basis, as said in many reviews in popular online nootropics forums, however, I believe this to be entirely wrong.  You should always take the minimum effective dosage and should cycle off of nootropics from time to time to avoid tolerance and addiction. Even with the safest and most subtle of nootropics, such as the racetams, there can be side effects on a long-term basis, so best to take in short bursts only. Some people choose to only take it when they feel they need a bit of extra help with memory and concentration, which in my honest opinion, is the best way to take nootropics, as it best lowers the risk of excess side effects.

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