What Are The Main Side Effects Of Using Sulbutiamine ?

Modern science has allowed the manipulation of molecules in order to form new substances that can perform specific functions. Sulbutiamine is one particular form of such substances. It was discovered in Japan after many research and studies on how to make Thiamine more efficient. Thiamine, also commonly known as Vitamin B1, is an essential nootropic vitamin. Deficiency of Thiamine can lead to different nervous system disorders, including beriberi, a brain disorder that can lead to confusion, hallucinations, and psychosis. Sulbutiamine is a synthetic molecule derivative of two modified Thiamine molecules that are bound together by a sulfur group.

Efforts in Japan to make a more useful and efficient thiamine derivative have led to its discovery. Sulbutiamine is considered to be a more efficient version of Thiamine since it is more effective in crossing the blood-brain barrier. This easy availability of Sulbutiamine makes it useful in increasing the levels of both Thiamine and Thiamine phosphate esters in the brain, which results in better pharmacokinetic properties. It has long been sold and used in the market as an over the counter nootropic due to its many benefits. Sulbutiamine side effects are extremely mild and most users report none that occur.


Sulbutiamine’s benefits are typical of the nootropic quality, which is to enhance mental ability and cognitive function. It is the only known compound to clinically cure asthenia, a disorder characterized by abnormal levels of physical weakness and complete lack of energy. As such, Sulbutiamine is an effective treatment for chronic fatigue, especially those that are brought on as associated with infections and other diseases. It may be used to simply improve wakefulness and alertness.

It is considered to be a nootropic stimulant. Sulbutiamine has the ability to improve memory function and cognitive ability and can also help improve moods and temperaments because of its anti-depressant effects. It has been shown to reduce psycho-behavioral inhibition, which are behaviors typically related to social anxiety, such as extreme shyness and other characteristics of major depressive disorders. It has even been implicated in the improvement of sexually related malfunctioning such as erectile dysfunction.

In more recent times, Sulbutiamine has also been used in the sports industry. Many athletes use this supplement as a legal form of performance enhancer due to its stimulant effects. It has been shown to increase physical effectiveness and well being, and it has also helped athletes with mental effectiveness in the field as well.

Recommended Dosage

More studies in regards to dosage effectiveness of Sulbutiamine is needed in human cases. However, there have been several human studies that have suggested a daily dose of 400mg of Sulbutiamine. Some manufacturing companies have recommended a maximum daily dose of 600mg. Some other users have suggested effective optimal dosage at 1000mg over a 24-hour period. Currently, there are no known ideal dosing regimens.

Whether Sulbutiamine is better taken with meals or without, or whether it is better taken as a single dose or in increments, is clinically unknown. As it is fat-soluble, Sulbutiamine has been recommended by some users to be taken with food, milk, or fish oil. Sulbutiamine may be taken in powder or pill form. However, it is not water-soluble, so it may not be as effective when mixed in with water or other liquids to make a drink. Sulbutiamine is generally safe to be stacked with other nootropics and is even recommended by some due to its typically short half-life. However, taking about twice the usual dosage will result in an overdose.

Side Effects

As with any supplementation, moderation is the key. Taking the proper dosage of Sulbutiamine will result in fewer or no adverse effects. Although, there have been reported cases of mild side effects due to an overdose of Sulbutiamine. Some of these may include headaches, nausea, and anxiety. It may also cause rashes or other mild skin allergies. In elderly patients, Sulbutiamine has been shown to present mild irritability. Excess dosages of this supplement may result in disruption of mood and sleep and even higher levels of anxiety. It has also been shown to suppress appetite.

Long-Term Use

Perhaps the most dangerous side effect of taking Sulbutiamine is tolerance. This supplement has a history of causing a quick tolerance build up, which is evident in diminished actions in mood and other nootropic effects. Some people have a tendency to become addicted to Sulbutiamine, while others do not. Some studies have shown that when Sulbutiamine was taken consecutively for just a little under two weeks, people have had to undergo a withdrawal that lasted between 2-5 days. Sulbutiamine side effects, when used long-term generally tend to increase in size, yet are still very maintainable according to our customer’s accounts.

It seems that when excessive dosages of Sulbutiamine are consumed, addiction is more likely to present itself, and withdrawal is likely to follow. Although it should not be considered as an addictive substance because of the lack of any psychoactive compound, research and history of use show otherwise. Therefore, long-term use of Sulbutiamine is not recommended for anyone, regardless of how it is used and what it is used for.

Short-Term Use

Sulbutiamine is best when used sparingly due to the possibilities of tolerance buildup. Short-term use is highly recommended for cognitive needs such as enhancing motivation, supporting mood and strengthening the memory function. Its benefits are immense when used properly and in short periods of time, and this will also eliminate any long-term dependencies.

Legal Status

Sulbutiamine is not manufactured or marketed in the United States, but it is available through many markets and channels online. Since it is not regulated by the Food and Drug Administration, it is legal to obtain as a supplement. As a matter of fact, Sulbutiamine is widely used and legal in over 30 countries. It is sold under different brand names such as Arcalion and Enercon. There is no prescription required to obtain Sulbutiamine. However, with the use of any supplement, it is still recommended to speak to a health care provider before beginning any dietary supplement regimen.

Final Thoughts

Sulbutiamine has many beneficial effects for its user as long as excessive use is avoided. Its basis as a vitamin derivative can have promising outcomes and may have significant implications in the future of pathological research. Sulbutiamine is an effective nootropic for those seeking to increase mental energy. As long as proper dosages are followed and the user is wary of addictive effects, Sulbutiamine is a good supplement for those who need it.

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