A Review Of The Benefits Of Using Sunifiram

What Is Sunifiram?

Sunifiram is a synthetic derivative of Piracetam which has a higher potency. It was first researched in 2000 and it shows anti-amnesiac properties that can potentially be a cognitive enhancer. It is being investigated at this time to be a potential treatment for Alzheimer’s and other diseases related to cognitive decline. Sunifiram has a low toxicity profile and it falls into the ampakine family of nootropic supplements. Sunifiram has been found to be highly effective for boosting memory function, attention span, learning, decision making, and alertness.


Sunifiram was developed in 2000 and it is one of the newest nootropics on the market at this time. The first studies of Sunifiram showed that it is a memory-boosting substance. It has only been on the market for a little over a year for public consumption, but it is now the most popular ampakine for casual nootropic users.


The majority of the people that have used or are currently using Sunifiram reported slight headaches that mostly stopped occurring after taking Sunifiram for a couple of weeks. Other common experiences were an amplified sense of smell, clearer vision, positive mood boosts and feeling more awake throughout the day without the assistance of caffeine. A few people did report more unusual experiences like increased libido and a strange fascination with staring at people. A typical Sunifiram review usually involves one’s experiences, some good some bad, and encompasses both cognitive benefits, and pesky side effects.


No human studies have been done on Sunifiram to date, but there have been several benefits noted without the studies. The benefits of Sunifiram that have been documented are enhanced memory, focus, heightened alertness and promotes better moods. It is also said to be responsible for alleviating stress, increasing learning ability, improving attention span, improving decision-making ability, and improving motor skills. People that have taken Sunifiram have reported an improvement in the ability to transfer short-term memory to long-term memory.

How Long Does Sunifiram Last?

According to the people that have used Sunifiram, the initial benefit kicks in within ten to fifteen minutes of consumption. It has been reported that it is not a gradual increase in alertness, but more like a bang. The benefits are reported to starting to wear out after approximately two hours and is completely gone by four hours.

Recommended Dosage

Since Sunifiram is more potent than Piracetam, you would need to take a smaller dose. The recommended dosage is 4 mg to 8 mg taken three times a day at most. Sunifiram works best when it is placed under your tongue. Some people take up to 10 mg at one time. Taking 10 mg at one time could increase the risk of side effects and could also cause tolerance to build faster.

Side Effects

There have not been any human studies done with Sunifiram as of yet, so all the side effects may not be known. The mild side effects that have been reported by people who have taken Sunifiram are headaches, anxiety or paranoia when Sunifiram wears off, nausea, restlessness, increased perspiration. The most common of these mild side effects are headaches, which can usually be counteracted by a choline supplement.

Other people who have taken Sunifiram have reported that they have eye twitches and heaviness of eyelids. Also, waking up with stuffiness in the ears. Increased anger response has been reported by people who are not typically angry people. And other people report a fascination with a certain color or sound. Another side effect that has been reported is insomnia. Some state that they have insomnia and that when they do sleep, they have nightmares and leads to a night of restless sleep.

Long-Term Use

With the lack of human studies done, the full extent of long-term effects is unknown at this time. The majority of the people that have been using Sunifiram since it came out on the market for public consumption reported that the most obvious effect of using Sunifiram long-term is on memory recall. It has been reported that long-term use of Sunifiram enables its users to remember occasions and details which they had forgotten long ago.

Short-Term Use

Along with a sense of alertness, great memory recall, and positive mood boosts, the use of Sunifiram does have a few reported negative side effects. These side effects are minor and can be treated easily. They include anxiety, headaches, nausea, and lack of sleep.


Sunifiram was discovered and studied in 2000 and has started being researched for Alzheimer’s treatment. Although human studies have not been done as of now, Sunifiram has been tested clinically in animals, rats, and mice specifically. Sunifiram has been reported to be four orders of magnitude more potent than Piracetam.

Injections of Sunifiram of 0.1 mg/kg have been reported to have cognitive enhancing properties that are comparable to 30 mg/kg injections of Piracetam in normal rats.

Injections of Sunifiram of 0.01 mg/kg are able to facilitate acetylcholine release in the prefrontal cortex of rats.

Injections of Sunifiram of 1 mg/kg has been reported to abolish the reductions seen when given after training sessions in mice with hippocampal-dependent memory impairments.

Induced amnesia has been noted to be reduced with Sunifiram injected doses 0.001 mg/kg and oral doses 0.01 mg/kg.

Sunifiram was not noted to have any effect on mice with depressive effects.

A study noting the efficacy of Sunifiram failed to find any overt toxic symptoms.

Online Reviews

Many reviews stated that the people taking Sunifiram have noticed alertness and better memory, as well as headaches. It has often been reported that it feels like a stimulant similar to Adderall. Some customer Sunifiram review logs are as follows:

“Been using it a while…i can focus things for longer…object’s color and shape come alive, enhanced, and sharpened. As far as a memory I can go back in time in my memories and trace sequence of events much more easily. Also, upon first taking Sunifiram there was a clearness of mind.” Carlos Fabery (www.nootriment.com/sunifiram-review)

“Upon receiving my Sunifram I was pleased to see it came with a lab report as well as a scoop and dosage instructions. I’ve tried a handful of nootropics and I say I was very pleased with my experience! This is definitely great stuff and I actually prefer it over my Adderall. Thanks, LiftMode you guys rock.” The Dream Within (www.amazon.com/dp/B00C7CF6RG)

“I received my Sunifiram much sooner than I expected, product came well packaged and in perfect condition along with lab tests for purity as described. After using this product for the last week or so all I can say is that I am in love. A great boost of energy along with feelings of happiness I have never experienced with nootropics. I have been taking 5mg of Sunifiram every morning with a small breakfast and I am never looking back! I get more done, I feel happier, I can remember small details that my job requires that I was never able to do before. I highly recommend Sunifiram to anyone looking for a great boost, with no crash, much further than caffeine could ever produce.” Collin (www.amazon.com/dp/B00C7CF6RG)

Is Sunifiram Legal?

It can be legally purchased in the United States, Canada, and the United Kingdom. If you want to purchase it in Australia, you are required to have a prescription. It is also banned for athletic competitions.

Final Thoughts

Sunifiram is the newest nootropic to hit the markets and it has hit with a bang. The people who have started using it seem to like it and prefer it over other nootropics. It is always best to discuss with your doctor and read up as much about it as you can before you start taking it as well.


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