What Are The Effects Of Tianeptine Use?

Tianeptine Effects

Tianeptine is a novel antidepressant drug that has been around for quite some time, but is yet to be fully understood by many on its functions, side effects, and results from use. This atypical antidepressant has shown efficacy in depressed patients especially those who are refractory to normal antidepressant treatment. It is reported to have less adverse side effects and reactions which make it a favorable option in comparison to other antidepressants.

Tianeptine takes relatively fewer days to begin seeing a transformation in terms of mood improvement. This is unlike other antidepressants which may take up to two weeks for their effects to be experienced, and in certain cases, it may even worsen the situation. It is available as a prescription drug in many places in Europe, Asia, and South America but is yet to be allowed in the United States and Canada. Effects of Tianeptine can be very potent, so always start with a low effective dosage of 12 mg.

Among anti-depressants and nootropic drugs, Tianeptine is one with the least negative side effects both in the long term and short term prospects. It has positive stimulating effects on the brain which improve alertness and memory and general moods.

Benefits of Tianeptine

Tianeptine effects are extremely potent, and these qualities, of increased energy, focus, and mood, can help one’s overall quality of life. Tianeptine is primarily used to treat heavy depressive disorders. It is also used in the treatment of asthma or irritable bowel syndrome because of its pharmacological properties. This antidepressant is more effective and popular with patients who are refractory to standard treatment. It provides a perfect alternative, which is far much effective and requires less time to improve moods. It has significantly fewer side effects and has shown to reduce anxiety levels too.

Due to its anxiolytic properties, it is useful in the treatment of anxiety caused disorders such as panic disorder. Additionally, Tianeptine has a beneficial effect on cognition in patients having cognitive dysfunction induced by depression. Among the varied causes of depression, Tianeptine has been found to reduce depression as a result of traumatic stress disorder and Parkinson’s disease. This is just as effective and safe like Fluoxetine and Moclobemide prescriptions which are used for this treatment.

In terms of tolerability with other forms of medication, Tianeptine has fared very well and reduces chances of constipation and dry mouth which are common side effects with other prescriptions. The less prominent side effects prove it to be safe and generally accepted in combination with other forms of treatment. Patients who have used it have reported more awareness and improvement in reaction time. They feel happier and more energetic once they use the drug.

Recommended Dosage

The dosage of this drug comes in 12.5 mg pills. It is generally recommended to take one or two pills three times a day. To ensure a smooth transformation for new users, it is suggested that the dose is taken in half in the morning and the remaining half at night. This should go on for some time until you are used to the drug, then you can begin the normal dosage. It is also advisable that you seek the guidance of a qualified physician who will prescribe the drug in reference to your medical history.

Side Effects

Compared to other antidepressants, Tianeptine has fewer side effects such as dry mouth, constipation, cardiovascular effects and appetite-stimulating effects which are quite common in other treatment. It is however suggested, to be among antidepressant drugs prone to causing liver damage. This concern has not been fully supported with concrete evidence and is therefore of limited quality at the moment. Other common side effects such as headache, dizziness, nausea, weight gain, dry mouth, constipation, irritability, and abdominal pain have a frequency of less than 1% which is very negligible.


Tianeptine has several generally accepted mechanisms of activity concerning its influences on the mind. According to recent research, it has been found that Tianeptine enhances extracellular concentrations of dopamine in the brain. Dopamine is responsible for mood-boosting in the brain through neurotransmitters pathways which lead to reduced anxiety and depression. It also has an effect on glutamate receptors which play an important part in reversing neuroplasticity often associated with stress. It causes serotonin produced in the brain to be reabsorbed which is why Tianeptine is an SSRE.

Safety Concerns

There are no real dangers associated with Tianeptine, although some research sources suggest that most anti-depressants cause cardiac arrhythmias. Abuse of Tianeptine is very rare, and the few found cases have been found in people with pre-existing substance abuse. Abuse of Tianeptine in order to achieve an anxiolytic state would lead to withdrawal symptoms in a person, and its severity would depend on the amount of dosage used.

Legal Status

Tianeptine has not yet been approved for medicinal use in the United States and Canada, which means there’s no prescription for it in the treatment of depression and anxiety. In countries such as France, Tianeptine has been used since the 1960s, where it was in fact discovered. It is also legal in Asia and South American countries. A possible reason why it is not yet allowed in most English-speaking countries is that initial research was carried out in French.

Final Thoughts

In the treatment of major depressive episodes, it is highly recommended because of its efficacy and no side effects. It will significantly reduce stress, sadness and relieve feelings of anxiety. It also boosts memory and increases alertness and improves reaction time. This nootropic is found as a prescription in some countries under the trade names of Coaxil, Stablon, Tianeurax, and Tatinol. It is a noteworthy try considering its far-reaching benefits which are more than just other anti-depressants. The main Tianeptine effects consist of, better mood, more energy throughout the day, a significant anti-depressant effect, and help in the cases of which Tianeptine is used for opiate withdrawal.

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