The Side Effects And Dangers Of Tianeptine Use

What Is Tianeptine?

Tianeptine, otherwise known as Coaxial, Retinol or Stablon, is a drug that is used as a common treatment for Major Depressive Disorder, along with other health complications such as irritable bowel syndrome and asthma. As a chemical compound, this drug is a tricyclic antidepressant that works primarily by affecting glutamate receptors along with neural efficiency. Since this type of drug has anti-anxiety and antidepressant properties along with a lack of cardiovascular and sedative effects to the body, it has also been used for the elderly who have alcohol withdrawals symptoms. This is because older people are much more sensitive to the adverse effects of conventional treatments such as psychotropic drugs. Tianeptine withdrawal symptoms resemble that of a low-dose opiate if it is taken in high amounts. The vast majority of users, however, do not experience Tianeptine withdrawal. If withdrawal should occur, something like N-Acetyl L-Tyrosine can work wonders for your recovery.


The primary mechanism of action of this type of drug is unlike any other on the consumer market. For those who are not aware, Tianeptine is considered as an SSRI, which are pharmaceuticals that mitigate the uptake of serotonin by affecting specific neurons- consequently leading to improved levels of serotonin uptake. It is for this particular reason that this specific type of drugs has shown great efficacy in the treatment of complications that range from depression to post-traumatic stress disorder. Furthermore, Tianeptine is a common medical solution for countless forms of mental disorders in France and many countries all over Europe. Users will also appreciate knowing the drug has no kind of tolerance or anabolic side effects on the body even after increased periods of use. Some other research evidence shows that the drug may also be beneficial in the treatment of obsessive-compulsive disorders along with social anxiety due to its relaxing effects on the central nervous system. Some strong evidence also exists that shows the drug is beneficial in the treatment of degenerative disorders such as cerebral aging, Alzheimer’s disease, and multiple sclerosis.


It is important to know that Tianeptine is beneficial in the mitigations of adverse complications and comparable to other medications such as imipramine and amitriptyline- but with reduces side effects. More so, this type of drug shows efficacy, in treating a spectrum of anxiety complications including PTSD (Post Traumatic Stress Disorder). More importantly, Tianeptine is an effective treatment for depression disorders such as Parkinson`s Disease and panic anxiety. Recent clinical studies have also established that this type of drug is at least as effective as amitriptyline- though Tianeptine is known to produce fewer side effects including constipation and dry mouth. Tianeptine withdrawal should not occur if the drug is taken in proper, lose dose of 12-24 mg per day, and if it is taken on a regular basis.

Recommended Dosage

The conventional dosage recommended for this drug is 12.5mg formulations. More so, most medical practitioners suggest that users consume that tablet two or three times in a day. Additionally, it is considered beneficial if you can split the dosage up to ensure the body has a regular supply of the drug. First-time users of the drug are also recommended to start with a smaller dosage and increase gradually upwards to feel the full effects of the drug. In some countries, the drug might be considered a controlled substance and requires a prescription from a medical professional. It is also important to avoid self-medication and consult a doctor before settling for the drug and its unique effects on the body.

Side Effects

Since this type of drug has mood enhancing properties of the body, the majority of researchers are concerned that it can lead to addiction to stronger drugs or perhaps overdependency in users. When compared to conventional antidepressant medication, tianeptine produces markedly sedative, appetite increasing and cardiovascular side effects on the body. A recent medical publication determined it is a drug that is most susceptible to causing liver damage. Other common side effects of the drug include dizziness, insomnia, nausea, headache, and even dry mouth.

Long-Term Use

Since this drug helps in the alleviate depression and mood disorders, some are concerned that there is a high chance of users developing addictions or excessive dependency on the drug. More so, some users have also reported some cases of insomnia and nightmares and extensive use of the drug. Tianeptine withdrawal will occur with long-term use, so it should be taken in short bursts, and on a very irregular basis!

Safety Concerns

Since this drug has significant side effects on the central nervous system, some users are likely to experience headaches, stomach upsets or even dry mouth. More so, consuming more than the recommended dose can lead to hepatoxicity (liver damage), which can then result in death or severe damage to the central nervous system. Furthermore, the drug works well with other conventional prescription drugs and can be taken with or without food. Dangers of taking Tianeptine are that in high amounts it can lead to withdrawal symptoms.


Tianeptine has been reported as an effective treatment for asthma and chest related complications. According to a study conducted in August 1998, Dr. Lechin Fuad and his team and the Central University of Venezuela were held on a host of asthmatic children. The 52-week controlled and randomized study of asthmatic children determined that children in the groups that received regular doses of the drug had reduced clinical visits and improved lung functions. Some years before, the researchers observed a strong relationship between serotonin in the plasma and the severity of asthmatic attacks in individuals. A 2005 study in Egypt showed that Tianeptine was an active treatment for men with erectile dysfunction and depression. This type of drug also has significant analgesic and anticonvulsant effects, according to a recent clinical study in Spain that concluded in 2007. Other studies have also shown that Tianeptine is beneficial for the treatment of fibromyalgia along with Attention Deficit Hyperactivity Disorder.

Online Reviews

Yohan Tomkins says

I experienced tumultuous ordeals as a child and its unfortunate to say that these events followed to haunt me later in my life. I suffered from depression and anxiety and disorders, and so I decided to go and visit the psychologist. While the medications worked, they only worked for a while and had considerable side effects on my body. However, after trying out this innovative drug, I am proud to say that it has changed my mood and my sense of well-being has also improved. What is more remarkable is the fact the drug works well on the body without side effects such as headaches or addiction.

Don Agebechukwu

If you have ever had a recurring alcohol addiction, will be aware of how tough it can be to quit without the withdrawal effects bringing your life as you know it a stop. I have tried countless forms of therapy, and most of them only work sometimes, but then I find myself falling back to my old ways. However, after the incorporation of Tianeptine into my recovery regime, I must say that the results are astounding. The drug not only works well with my other medication but is legal and helps alleviate the depression that was the leading cause of my alcohol addiction.




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