Cardarine (GW-501516) is a research chemical, first created by GlaxoSmithKline and Ligand Pharmaceuticals in 1992. Cardarine is sold as SARMs, Ostarine, LGD-4033, S4, etc. It is a PPAR agonist, meaning it binds to the PPAR (Peroxisome Proliferator-Activated Receptors) in the human body. The activation of PPAR in the body has momentous insinuation in refining cardiovascular health, metabolism (especially about reducing calories) and as an anti-inflammatory compound. It can protect the brain and heart, and recuperate muscle growth.
Cardarine was developed to avert and cure tumor formation in the colon, prostate, and breasts. It was principally created for health welfare and it works by activating similar pathways that the body stimulates when we workout. It was developed to treat obesity, diabetes, lipid strain, and heart health problems.
However, studies done in the early 2000s have found that GW 501516 and other PPAR agonists have also been able to rest metabolic ailments like obesity and diabetes through specific gene expressions.
Benefits of Cardarine
GW 501516 is the “ultimate endurance enhancer.” It provides insane energy levels which will help you push harder in the gym, increase intensity levels and bust through plateaus.
It reduces recovery time too and is known to deliver one of the cleanest energies. It gives you an overall sense of health and well-being.
Cardarine assists in losing weight by using fat stores for energy rather than carbohydrates. Furthermore, Cardarine helps with lipid strain and increases healthy cholesterol levels substantially.
Cardarine is used by athletes competing in different sports. For instance, endurance athletes may increase exercise endurance by stacking these PPAR receptors with the AMP analogue drug AICAR. As a result, the receptors will have a powerful ability to reach higher RPM’s throughout their runs without beating the extreme heart rate.
This will allow the runner/cyclist/swimmer, all competitors, to cheat their extreme heart rates and go longer without getting breathless. This makes Cardarine an excellent weapon to use in endurance sports.
Additionally, Cardarine can give the advantage to the bodybuilders in two ways:
- Its capability to burn fat.
- Its ability to aid the athlete in doing tougher and longer workouts without breathlessness.
Regarding obesity, Cardarine converses metabolic disorders in obese and pre-diabetic men by activating fatty acid oxidation. That is, it burns fat by increasing levels of glucose uptake in skeletal muscle tissue which changes the body’s metabolism to burn calories for energy instead of muscle or carbs. Exceptionally, it does all this without plummeting blood sugar levels as diabetic drugs do.
Your weight lifting sessions will be protracted. And you’ll feel more thrilled after taking this drug, eventually getting a lot more work done before you hit the gym each day.
GW 501516 prevents oxidative damage to the heart. It decreases the threat and severity of atherosclerosis. It increases levels of nitric oxide which defends against atherosclerosis.
It is also associated with the suppression of inflammation. Cardarine can activate PPAR which safeguards specific skin cells from enduring impulsive cell death during the wound-healing process.
For anabolic-androgenic steroid operators who like the drug trenbolone, Cardarine is eccentric at combating the adverse negative effects of “tren” and, thus, enhancing positive results.
The average dose for both men and women are 20 milligrams (mg) per day.
Cardarine will give assistance in both endurance and fat oxidation at 10-15mgs per day for an ultimate 8-week cycle. However, a dose of 20mg per day for 8-12 weeks is the recommended dose to get a complete finest outcome in and out of the gymnasium.
Some athletes like to use the entire 20-mg an hour before their workout period while others will split the dose into two halves, half in the morning and another half in the evening. Cardarine is a banned substance in a few spots, so it’s advisable for users to be careful with its use provided you’re a tested athlete.
That said, it is superlative to squirt the liquid into your mouth, swallow and then chase it down with some juice or water.
Cardarine is fundamentally free of side effect. Though some studies have shown a small increase in cancer rate in mice but not in humans, these studies were done for a very long time with contemptible doses but nowhere in mentioned any side effects in humans.
However, other studies have shown no significant link to cancer at all and even further studies have shown Cardarine reduction in tumor size. Therefore, it helped cure some cancers. The chemical compound has been dosed in human PPAR for some years and is only providing positive results on cancer treatments, liver function, and metabolic issues.
Side effects are rare with Cardarine, but as with all drugs, it should be consumed under the correct dosage. Since it is not a hormone, there is no need to be concerned about PCT or suppression.
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