N-Acetyl L-Tyrosine Dosage
N-Acetyl-L-Tyrosine (NALT) is one of the non-essential amino acids (“non-essential” meaning that a healthy body may synthesize it from other amino acids), which are the building blocks of protein in the human organism. The best N-Acetyl L-Tyrosine dosage normally varies from person to person and based on their specific needs. Apart from N-Acetyl-L-Tyrosine as well as its acronym NALT, it is also known as L-Tyrosine or Tyrosine. NALT as a supplement provides the organism with highly bioavailable L-Tyrosine. What makes NALT especially useful is its role in the building of two neurotransmitters, namely dopamine and norepinephrine. Typical dosage of the supplement range from 500 milligrams to 8 grams, taken daily (if higher amounts are consumed, it is done so in small amounts throughout the day). NALT, overall, is a fairly cheap drug.
Once ingested and processed N-Acetyl L-Tyrosine produces L-Dopa, which is an important precursor to dopamine, which in turn helps the building of more norepinephrine. Dopamine is an organic chemical present in the brain and rest of the body of the catecholamine group with wide implication on neurological and psychological health: learning, voluntary and involuntary muscle work (including fine movements), libido and sexual arousal, memory and memory recall, focus and efficiency in goal-oriented tasks of intellectual nature.
Norepinephrine (also called interchangeably noradrenaline, a synonym) is a neurotransmitter, which through his mode of neurological actions increases all aspects of vigilance and alertness, enhances the formation and retrieval of memory and improves learning and focus. All of the aforementioned actions, withstanding other complex aspects of neurochemistry in regulating psychological processes and mental performance are facilitated and may be enhanced by proper intake of N-Acetyl L-Tyrosine (NALT).
This is its quality that classifies it as a nootropic (‘mind booster”, “cognitive enhancer”). N-Acetyl-L-Tyrosine is quickly absorbed and is better utilized than L-Tyrosine supplements and kept in the body slightly longer.
Benefits
What are some of the main benefits of using N-Acetyl-L-Tyrosine? N-Acetyl-L-Tyrosine is used for the treatment of rare, but serious genetic disorder named phenylketonuria, in which the organism cannot produce enough Tyrosine. It may be utilized as an efficient appetite-suppressant, which, together with exercise and properly formulated diet has a palliative effect on obesity. Through boosting of the level of dopamine and noradrenaline it relieves general fatigue, has a use in the treatment of narcolepsy (sudden and common onsets of short sleeping episodes) as well as Parkinson’s disease which is partly ameliorated by an increase of dopamine levels. Much research shows that the best N-Acetyl L-Tyrosine dosage for improvement of overall brain health is 1500 mg per day.
Its well-studied stress-protective function is achieved through the effects of dopamine and norepinephrine via their effects on boosting of mental stamina. It has been proven in a study using individuals performing strenuous military training program, during which higher perceptual performance (memory, task-solving) was markedly better than in the placebo group. Milder forms of depression are diminished by this natural form of increase of both neurotransmitters.
Indeed, currently, most efficient prescription-only antidepressants like Bupropion (stimulative; acts as a dopaminergic), as well as Mirtazapine (calming; acts as a powerful antidepressant and sleep aid by interacting with norepinephrine), operate by increasing intra-synaptic quantities of the aforementioned neurotransmitters.
N-Acetyl-L-Tyrosine, by securing greater natural production of both dopamine and norepinephrine helps to alleviate some forms of depression without the necessity of using synthetic drugs. Some circles promote NALT for treatment of Alzheimer, but medical studies on this potential use are inconclusive.
Recommended Dosage
With regard to strictly nootropic, mind-boosting performance, the stress-protective action and role in the production of norepinephrine and especially dopamine is the key neurochemical cores of the mind-improvement. Dopamine is generated by N-Acetyl L-Tyrosine (NALT) via its metabolic conversion to L-dopa, a precursor of Dopamine. Stress, prolonged sleep deprivation, hard physical activity have the exhausting effect that decreases functions of the mind and properly taken N-Acetyl L-Tyrosine enables the user to perform well on subsequent intellectual, learning and professional tasks.
This makes N-Acetyl-L-Tyrosine ideal for populations of students, academics and other professionals who practice physically-demanding sports (team sports, body-building). Anxiolytic activity is seen in the recommended doses, although of a more subtle level than dedicated pharmacological solutions as well as other nootropics (i.e. Aniracetam, with which NALT can be safely stacked). N-Acetyl-L-Tyrosine best effects on cognition, learning, data-processing and keeping focus are evidenced in healthy persons with or without a history of immediate stressful activities.
It is noteworthy that the synthesis of melanin, another substance necessary to humans provides protection against neurotoxicity, especially a chronic intake of minuscule, yet dangerous metals, whose presence in the atmosphere is common nearby industrial zones. The combined effect of the processes unleashed by N-Acetyl L-Tyrosine is therefore very helpful in “burnout” syndrome, often felt by professionals who are involved in complex tasks demanding mental performance. It can be summarized that it enhances the influx of data by sensory pathways, strongly enhances attention, boost the formation and retrieval of both the long term as well as working memory.
For most users, supplementation in the dosage range from 300mg to 500mg should be sufficient for a nootropic effect, which may take a couple of days to be fully felt. For the treatment of neurological diseases, your dosage must be established in consultation with a doctor. In order to prevent side-effects, it is recommended that the dosage for boosting and optimizing mental performance should not exceed 1,500mg in 24 hours.
Side Effects
Side-effects of N-Acetyl-L-Tyrosine are extremely mild, even in much higher dosages than those recommended. Headaches and nausea seem to be most common, but mostly transitory side effects. It should not be given to children and it should be completely avoided with the use of powerful dopaminergic stimulants, MAO inhibitors or concomitant use of L-dopa.
Its safety in pregnancy and lactation has not been established, so avoiding this supplement is recommended for those situations. Another state in which N-Acetyl L-Tyrosine supplementation should be avoided or closely followed by a doctor is any problem affecting the thyroid gland. However, in a retrospective of all studies and plenty of anecdotal evidence as well, properly dosed NALT is a substance with an excellent safety profile.
Is N-Acetyl-L-Tyrosine Legal?
FDA (Food and Drug Administration) as a chief regulatory body in the U.S. has not classified N-Acetyl-L-Tyrosine as a “medical drug” and in few instances discouraged manufacturers in the US to label it as such. However, due to the fact that it is a naturally occurring human amino-acid, its production and distribution are only limited to providing proper labeling as a supplement. In the U.S., under the current legal status that is unlikely to change, the end user may legally purchase, possess and use N-Acetyl L-Tyrosine.
If there’s an intention to purchase it or carry the supplement abroad, it is advisable to check the legal status in the country of choice, where it may be a prescription drug.
Final Thoughts
N-Acetyl L-Tyrosine (NALT) is the most superior way of delivery of L-Tyrosine, which a natural and obligatory ingredient for the function of the human organism, both physically and psychologically. Supplementation is an affordable way to feel its nootropic benefits without the alternative of greatly modifying the diet.
The necessity of L-Tyrosine as a precursor of dopamine and norepinephrine cannot be overstated in light of all-pervading effects on the cognitive functions produced by both transmitters. With a high safety margin, easy affordability as well as a vast number of possibilities for stacking, especially with racetam nootropics, NALT is a basic nootropic which can be carefully adjusted with other supplements for a maximal effect. Its effects are more apparent when one is collaterally exposed to high-level of stress during learning, task-solving and other engagement that needs boosting of mental performance, especially memory, focus and speed of thought, combined with clarity.
All of these effects synergistically provide higher mental stamina in ever-increasing modern-day necessities that may cause physical and psychological fatigue in otherwise healthy adults. One should not think that supplementation with N-Acetyl L-Tyrosine should be taken only in ad-hoc situations of extreme stress. Its natural process of stress-reduction and mind-enchasing qualities provide every individual with a better understanding of the environment, of immediate surroundings and one’s priorities.
Improving the way one’s brain works by protecting it from effects of common and undesirable neurotoxic substances and healthy boosting its higher activity conducive to optimum, streamlined and focused grasping of the surrounding and solving problem are modes of actions that make N-Acetyl-L-Tyrosine a worthy candidate for improved health and mind.
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