The Effects And Results Of A Noopept Megadose

What is Noopept?

Now as the owner of a Smart Drugs website, I’ve taken just about every nootropic combination you can possibly think of (I spend all day in a warehouse bottling this stuff….it’s basically like being in a candy store of nootropics and it’s all free…how could I not? :)) I’ve played with dosages, stacks and every stimulant/racetam combo you could imagine. One thing I’d always been reluctant to do, however, is the so-called “mega-dose” even though I’ve written about it extensively. As I don’t consider myself a hypocrite, it was time to give it a shot.

Noopept is a potent psychoactive nootropic drug with a wide range of cognitive benefits. The drug is largely a peptide-based racetam and acts on specific regions of the brain that help to activate neurotransmitters, namely glutamate, dopamine, Seratonin, and norepinephrine. Noopept is used by students, athletes, and executives looking for a boost in the day to day activity, and is best if taken with a stimulant, such as Adrafinil.


Benefits of Noopept concern those cognitive processes of which allow higher order thinking. These are things like memory, mood, focus, and energy levels-and typically concern higher levels of specific neurotransmitters in the human brain. Noopept is a fantastic nootropic drug..but has a catch-the drug must be taken alongside a choline source in order to work properly. A “Noopept megadose” is really not recommended…like at all…with Piracetam and Aniracetam or whatever sure, but I wouldn’t recommend it with Noopept (the medical literature, however, states that if enough choline is taken with it…no adverse effects should occur.) A Noopept megadose typically is in a dosage of 50-100 mg taken at once.


As stated in the former, the proper dosage of Noopept is one that is around 10-30 mg. A Noopept Megadose is anywhere from 50-100 mg.


Research on Noopept in mice has shown that the drug helps to aid cognition in areas critical to thought. Research on the Noopept megadose has come back as stating that a dose of nearly 20-50 times the recommended amount would need to be taken in order to cause an overdose.

My Personal Review

My personal review of the infamous Noopept mega-dose is that…quite frankly, it works, and quite well actually. There are however a few exceptions to the rule that must be in place in order for the drug to work properly:

  • Be in a good mood when you take your 50-100 mg dosage. 

Noopept is a highly mood dependent drug, this means, it exasperates your emotions. If you’re feeling like    shit….a huge Noopept megadose is going to make you really feel that way. If you feel at least at baseline, or very good, Noopept will exaggerate this. Don’t take Noopept to get into a good mood, take Noopept to make a good mood that much better.

  • Choline, Choline, and Even more Choline on top of that Extra Scoop of Choline.

Make sure you take plenty of Choline with this, or it won’t work as well as it could and will give you a headache/potential side effects. How much you ask? While I can’t say definitely, in my personal experience, 250mg of CDP Choline per each 20mg of Noopept will work well.

Frequently Asked Questions

  • Are There Any Downsides?

Yes, risk..and headaches if not enough choline is taken.

  • How Can I Get This Nootropic Drug?

Buy it right here from our website.

  • Any Long-Term Issues I Should Be Worried About?

Nope-not unless you’re taking a mega-dose on the daily or something dumb like that…

  • Should I Cycle This?

Yes. Weekend breaks are the best (5 days on, 2 days off). In addition, take one week off out of every month.

Final Thoughts

Noopept on its own has some real potential to it as a nootropic drug. Be careful if you decide to megadose this, it’s strong enough as is!

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