Adrafinil Liver Toxicity-how to safely use this nootropic

Adrafinil Liver Toxicity

What is Adrafinil?

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In short, it is a drug that fits in the Nootropic classification, yet it is much more powerful than virtually any other drug of its type. Typically, it is used to help people stay awake. However, as more and more people have started using it, they are discovering that it can be used for a number of other things. For example, it works exceptionally well for people who work odd schedules that disrupt their sleep cycles. It also works equally as effectively for individuals that have to concentrate for long periods of time with little or no break in between their duties. As a result, it is not totally unlike the other types of Nootropic drugs that are available. However, it is more powerful. This ultimately affects the way people feel when they take it, as well as any potential side effects. It also affects the dosage.


There are actually a lot of different benefits that a person can get by taking this drug. As previously mentioned, it was originally designed to help people stay awake. Therefore, it is excellent in that particular role. People that take it are often able to stay awake and alert for hours beyond what they would normally experience. This can have a dramatic impact on the amount of work that a person is able to get done, especially when a person has a scheduled that is busier than normal or they work long hours. It also has the capability to enhance a person’s mood, effectively stabilizing negative thoughts and feelings and helping them feel more upbeat. Ultimately, it is able to produce better cognitive performance, allowing people to focus for longer periods of time and have improved recollection over the material that they have just digested.

Side Effects, how to mitigate these along with Liver Toxicity

Even the safest drugs can have side effects, especially when people take dosages that are excessive or they take the medication too frequently. By the same token, people that are very sensitive to medications may experience increased side effects while those that are less sensitive experience little or nothing at all. The side effects that are

most typically associated with this particular drug are anxiety, issues with the skin such as irritation and stomach pain. Many people do not experience side effects when they take the drug as recommended. Even those that do experience side effects typically report that they subside or are completely eliminated shortly after beginning the drug.


More often than not, people use this product to stay awake. It comes in especially handy for those individuals who are cramming for a test and they have to stay awake all night or for individuals that work night shifts. It is also very effective for those individuals who work rotating shifts because otherwise, they are virtually incapable of regulating their sleep wake cycle. This is something that helps them remain alert when they have to be as opposed to going through their entire shift in a fog. Some people use it to digest more information while they are studying or working on a large project at work. Some people find that it helps them work through these types of tasks much more quickly, so they use the medication to do exactly that. In some cases, people are able to get almost twice as much done in the same amount of time and they are better able to comprehend and recall everything that they take in. It also helps people think more clearly, so it is sometimes used to help people who are making complex decisions.

User Reviews

Virtually every person that uses it says that it works better than most of the other Nootropic drugs that are available. It is more powerful, so it takes a smaller dosage to achieve the same effects. In addition, many people report fewer side effects with this particular drug than they do with the other Nootropic products. Overall, most people find that it is one of the best acting drugs of its type. When people did report side effects, they reported that they were generally mild and that they did not last very long. As a result, many people have found that they can get better results with this product than they can with any of the other Nootropic drugs, not to mention the fact that they have to take less of the medication in order to achieve the superior results.


When it comes to the dosages, everyone reacts differently so it is important to start out with the smallest dose possible and then gradually build up to higher doses if that is what is required to get the desired results. Because this is a more powerful Nootropic than other products of its kind, most people start out with 150 mg. Some of them eventually build up to 300 mg after their body becomes accustomed to this drug. It is recommended that the dosage, whatever it may be, be split over three equal doses for the entire day that totals the number of milligrams a person wants to take, not to exceed 300 mg. If a person experiences undesirable side effects, the dosage should be cut back. On the other hand, if a person is not getting the results that they expected to get, it is acceptable to gradually increase the dosage as long as they do not exceed the 300 mg daily maximum. Typically, it is taken in powder form but in some cases, it is possible to find it in capsules as well.

Long-Term Effects

In the long term, people can expect to be more productive. Because this is a drug that helps people stay awake for longer periods of time while simultaneously helping them focus their attention more accurately, productivity levels can increase dramatically. The longer that a person takes the drug, the more that these effects can be seen. However, it is important to note that taking the drug for excessive periods of time or taking excessive doses can result in potential liver damage. There is still a great deal of research that needs to be done on this topic, but there is a lot of evidence to support the hypothesis that this Nootropic may have an adverse impact on the liver when it is taken improperly. Therefore, it is important to use caution when taking it in the long term.

Short-Term Effects

In the short term, people notice that they are more alert, that they are able to concentrate better and that they are capable of staying awake for very long periods of time without feeling sluggish. Typically, they start to feel

the effects within about 45 minutes to one hour after they take the initial dose. This is helpful for any individual that has to work an unexpected shift with very little sleep or when someone is preparing for an especially involved task that is going to require them to spend several hours in preparation. Better yet, the drug is able to achieve the short term effects without making people feel jittery, nervous or irritated in most cases. The rare exceptions are those individuals who feel an increased level of anxiety when they take it.

Is Adrafinil legal?

The short answer to that question is yes. The drug was originally developed in France and since that time, it has been discontinued and is no longer available for use there. However, in the United States, it is widely available for purchase. It does not require a prescription in order to get the drug, nor is it considered a controlled substance so it is not regulated by any government agency. While it does not have approval through the Food and Drug Administration, it is basically considered to fall in the same line as other Nootropics or herbal supplements. While it does not have expressed approval, it is widely available, as safety concerns in the United States have not been great enough to warrant further regulation on this particular product.

Adrafinil Liver Toxicity

As previously mentioned, there is some concern that this drug can cause liver damage, especially when a person takes it for long periods of time or takes excessive doses. It happens because the liver over metabolizes the drug, effectively causing toxicity of the liver. When people take only the prescribed doses or they refrain from taking it for long periods of time, the chances that they can have an adverse impact are far less than for those individuals that take large doses on a daily basis for several months or even years at a time.

Adrafinil vs. Modafinil

While this particular drug works in almost exactly the same fashion as Modafinil, it works much more efficiently. It is much stronger, so it works better in most cases. In addition, it usually is able to get the job done without causing some of the side effects that are typically caused by the use of Modafinil. With that being said, Adrafinil works better for some individuals while Modafinil works better in other cases. As a result, it is up to the individual to decide which one is more effective for their particular needs.

Adrafinil History

This drug was developed in the 1970s in France. It was developed by a group of scientists who eventually were able to make it available for commercial use. At the time, a prescription was required in order to obtain it in France. Many people touted its benefits but over a period of time, officials in the area became concerned that the drug was causing more harm than good. Eventually, they made the decision to ban the substance because they felt that the risks associated with taking it outweighed the potential benefits. In 2011, it was discontinued. Since that time, it has become widely available in the United States as a nutritional supplement.

Adrafinil Research

The research began with the scientists that developed the drug. They were working for a pharmaceutical company with the express purpose of making it available on a commercial level, which they accomplished in 1986. While initial research was promising, concerns about potential liver damage have tempered the excitement somewhat. However, there is still a lot of potential for this drug, especially when it is taken in carefully monitored amounts.

Final Thoughts

Every person reacts differently to certain drugs. As a result, a number of people can expect to have excellent results from taking this particular drug while some others will find something else that works better for them. Overall, it has a lot of potential. As is the case with most drugs, it can have undesirable side effects when misused. As long as it is taken correctly, most people can expect to take it safely.


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